Yintoni enokuyenza iGazi eliBlue le-Horseshoe Crab

Unonkala weHorseshoe, isidalwa saselwandle esingenabungozi kwaye samandulo, sidlala indima ebalulekileyo kwindalo, ukuze sibe kukutya kofudo nookrebe kwakunye neentaka zaselwandle.Njengoko imisebenzi yegazi layo eliluhlaza yafunyanwa, unonkala wehashe naye uba sisixhobo esitsha sokusindisa ubomi.

Ngoo-1970, izazinzulu zafumanisa ukuba igazi elizuba loononkala behashe liyakujika xa lithe lachanabeka kwibhaktiriya ye-E. coli.Kungenxa yokuba i-amebocyte kwigazi eliluhlaza lonkala wehashe inokusabela kunye ne-endotoxins, izinto eziyityhefu ezikhutshwe yi-E. coli kunye nezinye iibhaktheriya ezi-gram-negative ezinokuvelisa iimpawu ezinzima kubantu abavelele njengomkhuhlane okanye i-stroke esophayo.

Kutheni igazi eliluhlaza likankala wehashe linemisebenzi enjalo?Isenokuba ziziphumo zendaleko.Indawo ehlala ihorseshoe crab igcwele ibhaktheriya, kwaye unonkala wehashe ujongene nesoyikiso esiqhubekayo sosulelo.I-amebocyte kwigazi eliluhlaza lonkala wehashe idlala indima ephambili ekulweni usulelo, kuba ngenxa ye-amebocyte, igazi layo eliluhlaza linokubophelela ngoko nangoko kwaye lijike malunga nokungunda, iintsholongwane kunye ne-endotoxins yebhaktiriya.Yinkqubo yomzimba yokuzikhusela yoononkala ebangela ukuba igazi likanonkala libe luncedo kushishino lwethu lwezonyango.

Ngenxa yokukwazi ukubopha kunye nokujika, igazi eliluhlaza lonkala wehashe lisetyenziselwa ukuvelisa i-limulus amebocyte lysate, uhlobo lwe-lyophilized amebocyte lysate.Kwaye iimveliso eziveliswe nge-amebocyte ukusuka kwi-horseshoe crab phantsi kweendlela ezahlukeneyo ziyaphuhliswa.Okwangoku, kukho ubuchule obuthathu obusetyenziswayo ukubona i-endotoxin yebhaktiriya ngokusebenzisa i-lyophilized amebocyte lyate, oko kukuthi ubuchule bejeli-clot, ubuchule be-turbidimetric kunye nobuchule bechromogenic.Xiamen Bioendo Technology Co., Ltd. abavelisi lyophilized amebocyte lysate ngezi ndlela zintathu.


Ixesha lokuposa: Feb-28-2019